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Using a machine-learning algorithm, MIT researchers have identified a powerful new antibiotic compound. In laboratory tests, the drug killed many of the world’s most problematic disease-causing bacteria, including some strains that are resistant to all known antibiotics. It also cleared infections in two different mouse models. The computer model, which can screen more than a hundred million chemical compounds in a matter of days, is designed to pick out potential antibiotics that kill bacteria using different mechanisms than those of existing drugs. “We wanted to develop a platform that would allow us to harness the power of artificial intelligence to usher in a new age of antibiotic drug discovery,” says James Collins, the Termeer Professor of Medical Engineering and Science in MIT’s Institute for Medical Engineering and Science (IMES) and Department of Biological Engineering. “Our approach revealed this amazing molecule which is arguably one of the more powerful antibiotics that has...

The mediocre teacher tells. The good teacher explains. The superior teacher demonstrates. The great teacher inspires. ’ A teacher has the power to transform souls and touch someone’s life in a positive way. It is one of the noblest of professions that deal with life-changing and destiny-altering powers. The teacher has the present as raw material on which she will finally carve and design the future … the children. It’s an ever evolving yet challenging and lifelong learning environment of which we are an integral part. Teaching is a chance to touch someone’s life in a positive way. Teachers are the pillars of society for they educate and mould the future citizens of a country. Teaching, like any other activity, emerges from ones inwardness. Motivating and exciting students is the key. Passion for teaching is innate. At the core of caring relationships are positive and high expectations that not only structure and guide behaviours, but also challenge students to perform what they believ...

Two roads diverged in a wood, and I— I took the one less traveled by, And that has made all the difference. —Robert Frost, 1916 In his poem “The Road Not Taken,” Robert Frost famously wrote about choices. For graduate students in physics, the most familiar road is the academic path, but many other career paths are available to PhD physicists—far more than Frost’s two roads. According to NSF’s Survey of Doctorate Recipients, almost half of the 130 000 PhD physical scientists living and working in the US in 2017 were employed in the private sector, about 40% were employed in academia, and 9% worked in government settings In this article we examine the different career paths of PhD physicists working in private industry, academia, and government, and we describe what physicists in different sectors find rewarding about their chosen careers. In the first-ever 10-year follow-up survey of physics PhD recipients, the Statistical Research Center at the American Institute of Physics (AIP), whic...

Physics is an exploratory science. New experiments in physics change or expand our existing knowledge in one way or another. Let us find out how this has happened in history. 10. Galileo's Tower of Pisa experiment Before Galileo, a majority of people used to follow the teachings of ancient Greek philosopher, Aristotle, who had proclaimed that different weights when dropped from same height experienced different amounts of attraction from the Earth thus falling at different speeds. It is said that in 1589 Galileo climbed atop Tower of Pisa and dropped two objects of different masses in order to debunk Aristotelian belief. In 1971, astronaut David Scott re-created Galileo's famous experiment on the moon by dropping a hammer and a feather simultaneously. 9. Faraday's law of induction A sudden movement of a magnet through a coil produces a reading on the galvanometer meaning that a changing magnetic field can induce an electric current in the coil. This observation was first ma...

A couple of weeks back I posted an answer to a question from a Twitter follower’s child, who asked “How Strong Is Space?” That was fun, so here’s another kid-question answered, this one from my own eight-year-old who goes by “The Pip” for Internet purposes. The other night, he asked “Why can’t atoms touch each other?” I’m not sure the exact reason why he asked this, but the phrasing suggests it’s related to the observation that there’s almost always some microscopic empty space between things that appear to be touching on a macroscopic scale. Possibly it’s even connected to the “Atoms are mostly empty space” idea that Ethan talked about recently. The short and simple version of the answer is that it’s not really correct to think of atoms as solid objects like little balls that can be forced into physical contact with one another. Most of the “size” of an atom is just the electron cloud that surrounds the nucleus, and that’s not a solid thing— it will shift around in response to electri...

As someone who derives significant income from writing for money, I end up spending a fair bit of time reading writing advice. Not because I'm in need of tips, myself-- after many years of this, I've got a routine that mostly works for me. Rather, I'm looking for good advice to pass on to other people, because I get asked for advice on a regular basis, and I don't really have much of my own to offer. That's how I came to read this advice post from Alyx Dellamonica, making an analogy between figuring out how fiction works and trying to learn about cars from a junkyard. I like the junkyard analogy quite a bit, but along the way she makes a couple of passing mentions to physics that I absolutely hate. Here's the first: With the arts, you not a physics professor laying out a formula, some cut-and-dried procedure for which there is one satisfactory answer. You’re not showing someone how to paint the perfect yellow line down the middle of a strip of road, or fly an ai...

PHILOSOPHY OF LIFE ______________________________________________________________ Saddam Leonardo Kap ________________________________________________________________________ You are here not because of your future but past.   _____________________________________________________ T he thing that I want to share is, let’s understand it by an example. Suppose you are A, and in past, u had a relationship with B. Now in present u have an amazing and lifelong relationship with C. Now what do u think at this point is, the relationship with B was lousy, it was meant to have vanished, and it was terrible. It happens well that that relationship never worked out. I am now too happy and I will not repeat that mistake. I want to throw that relationship as if I was sick of it like it was a dark era or something like the worst thing ever happened. Now let me stop this here and give you some deep insight into that relationship at that time. In present moment whatever you are...